{"id":36264,"date":"2025-07-30T08:00:00","date_gmt":"2025-07-30T06:00:00","guid":{"rendered":"https:\/\/www.dexeus.com\/fertility\/blog-fiv\/infertilitat-masculina-les-causes-menys-conegudes\/"},"modified":"2026-03-23T11:36:29","modified_gmt":"2026-03-23T10:36:29","slug":"infertilitat-masculina-les-causes-menys-conegudes","status":"publish","type":"post","link":"https:\/\/www.dexeus.com\/fertility\/ca\/blog-fiv\/infertilitat-masculina-les-causes-menys-conegudes\/","title":{"rendered":"Infertilitat masculina: les causes menys conegudes"},"content":{"rendered":"

<\/h2>\n

El primer pas per esbrinar si un home t\u00e9 un problema d’infertilitat \u00e9s dur a terme un seminograma. Segur que el nom et sona o has sentit parlar d’aquesta prova. \u00c9s molt senzilla: consisteix a obtenir una mostra de semen i analitzar diversos par\u00e0metres com el volum, la concentraci\u00f3, la mobilitat i la morfologia dels espermatozoides.<\/p>\n

En la majoria dels casos \u00e9s suficient per detectar qualsevol alteraci\u00f3. No obstant aix\u00f2, un 15%<\/strong> dels homes inf\u00e8rtils<\/strong> presenten un seminograma amb valors seminals \u201cnormals\u201d<\/strong>, segons l’Organitzaci\u00f3 Mundial de la Salut (OMS). La ra\u00f3 \u00e9s que, a m\u00e9s de les alteracions en els par\u00e0metres que valora el seminograma, hi ha altres factors que tamb\u00e9 poden provocar infertilitat, com l’exist\u00e8ncia de desequilibris hormonals, problemes testiculars<\/strong> com la varicocele, disfuncions a nivell reproductiu<\/strong> (abs\u00e8ncia o obstrucci\u00f3 d’algun conducte) o malalties<\/strong> que afecten la producci\u00f3 d’espermatozoides.<\/p>\n

Altres causes menys conegudes per la poblaci\u00f3 en general s\u00f3n les afeccions gen\u00e8tiques<\/strong> i la fragmentaci\u00f3 de l’ADN esperm\u00e0tic<\/a><\/strong>. Aquesta \u00faltima es refereix a la pres\u00e8ncia de petits trencaments \u2013zones fragmentades\u2013 en les cadenes que conformen el material gen\u00e8tic (ADN) dels espermatozoides. Aquestes fragmentacions poden comprometre la qualitat i funcionalitat dels espermatozoides.<\/p>\n

Encara que en un principi pugui semblar sorprenent, es tracta d’un problema m\u00e9s com\u00fa<\/strong> del que es pensa. Diversos estudis han demostrat que els homes inf\u00e8rtils presenten nivells m\u00e9s elevats de fragmentaci\u00f3 de l’ADN esperm\u00e0tic en comparaci\u00f3 amb els homes f\u00e8rtils, la qual cosa pot afectar tant la probabilitat d’aconseguir un embar\u00e0s de manera natural com a l’\u00e8xit de les t\u00e8cniques de Reproducci\u00f3 assistida (TRA).<\/p>\n

No obstant aix\u00f2, existeixen casos en qu\u00e8 malgrat presentar aquest tipus d’alteraci\u00f3 alguns homes aconsegueixen concebre<\/strong> i tenir fills sans<\/strong>. De fet, si l’\u00f2vul \u00e9s de bona qualitat pot arribar a reparar parcialment aquestes fragmentacions en l’ADN esperm\u00e0tic, un fet que millora les possibilitats d’\u00e8xit reproductiu.<\/p>\n

Qu\u00e8 provoca la fragmentaci\u00f3?<\/h3>\n

Les causes que poden provocar la fragmentaci\u00f3 de l’ADN dels espermatozoides s\u00f3n m\u00faltiples: infeccions o episodis de febre alta, tractaments farmacol\u00f2gics, l’exposici\u00f3 a contaminants ambientals, el tabaquisme, l’estr\u00e8s oxidatiu cel\u00b7lular o una edat paterna avan\u00e7ada (ser major de 45 anys).<\/p>\n

\u201cEn la majoria dels casos, aquest problema pot abordar-se efica\u00e7ment i revertir la fragmentaci\u00f3 mitjan\u00e7ant canvis en l’estil de vida, tractaments antioxidants o, simplement, reduint el temps d’abstin\u00e8ncia sexual\u201d, explica Marta Ballester<\/a><\/strong>, responsable del Laboratori d’Andrologia de Dexeus Dona<\/strong>. A m\u00e9s, en el laboratori d’Andrologia comptem amb t\u00e8cniques avan\u00e7ades de selecci\u00f3 esperm\u00e0tica que permeten triar espermatozoides amb menor \u00edndex de fragmentaci\u00f3.<\/p>\n

Malgrat que aquestes mesures no s’aconsegueix una millora significativa, existeix l’opci\u00f3 de realitzar una bi\u00f2psia testicular<\/strong> per obtenir espermatozoides directament del testicle que presenten menor taxa de fragmentaci\u00f3 respecte als espermatozoides de l’ejaculat. Aquests poden utilitzar-se en un procediment de microinjecci\u00f3 intracitoplasm\u00e0tica d’espermatozoides (ICSI) per inseminar l’ov\u00f2cit, dins d’un tractament de fecundaci\u00f3 in vitro<\/em> (FIV).<\/p>\n

T\u00e8cniques diagn\u00f2stiques<\/h3>\n

Per avaluar si una mostra de semen presenta una elevada fragmentaci\u00f3 de l’ADN existeixen diferents t\u00e8cniques diagn\u00f2stiques. En el nostre centre realitzem el test de Dispersi\u00f3 de la Cromatina Esperm\u00e0tica (Sperm Chromatin Dispersion<\/em>, SCD) i la t\u00e8cnica COMET<\/strong>.<\/p>\n

El test SCD \u00e9s una t\u00e8cnica r\u00e0pida i senzilla que permet determinar el nivell general de fragmentaci\u00f3 de l’ADN esperm\u00e0tic, mentre que la t\u00e8cnica COMET ofereix una an\u00e0lisi m\u00e9s detallada, en diferenciar el percentatge de zones que presenten ruptures o segons el tipus de trencaments: de cadena senzilla<\/strong> o cadena doble<\/strong>. La fragmentaci\u00f3 de cadena senzilla s’associa amb una menor probabilitat d’aconseguir un embar\u00e0s natural, mentre que si \u00e9s de cadena doble es relaciona amb un major risc d’avortaments espontanis i, en els tractaments de Fecundaci\u00f3 in vitro<\/em>, amb una pitjor qualitat embrion\u00e0ria. \u201cDiferenciar el tipus de fragmentaci\u00f3 senzilla o doble, permet personalitzar<\/strong> millor el tractament a seguir\u201d, puntualitza Marta Ballester.<\/p>\n

En el nostre centre comptem amb una Unitat especialitzada en Salut sexual masculina<\/a><\/strong> i un Laboratori propi d’Andrologia<\/a><\/strong>, que treballa en coordinaci\u00f3 amb el Laboratori de Fecundaci\u00f3 in vitro<\/em> i el nostre equip del Servei de Reproducci\u00f3 Assistida. Tot aix\u00f2 agilitza tant la realitzaci\u00f3 de les proves com el diagn\u00f2stic, i, per tant, el tractament. A m\u00e9s, oferim un estudi de fertilitat conjunt de parella<\/a><\/strong>, que permet realitzar un estudi m\u00e9s complet en casos d’infertilitat.<\/p>\n

Esperem que aquest post t’hagi resultat \u00fatil!
Si vols fer alguna consulta o ampliar la informaci\u00f3 pots demanar cita amb la Unitat de Salut Sexual de l’Home.<\/p>\n","protected":false},"excerpt":{"rendered":"

El primer pas per esbrinar si un home t\u00e9 un problema d’infertilitat \u00e9s dur a terme un seminograma. Segur que el nom et sona o has sentit parlar d’aquesta prova. \u00c9s molt senzilla: consisteix a obtenir una mostra de semen i analitzar diversos par\u00e0metres com el volum, la concentraci\u00f3, la mobilitat i la morfologia dels […]<\/p>\n","protected":false},"author":2,"featured_media":36265,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,64],"tags":[],"class_list":["post-36264","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar","category-uncategorized-ca"],"yoast_head":"\nInfertilitat masculina: les causes menys conegudes | Dexeus Fertility<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dexeus.com\/fertility\/ca\/blog-fiv\/infertilitat-masculina-les-causes-menys-conegudes\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Infertilitat masculina: les causes menys conegudes | Dexeus Fertility\" \/>\n<meta property=\"og:description\" content=\"El primer pas per esbrinar si un home t\u00e9 un problema d’infertilitat \u00e9s dur a terme un seminograma. 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